Drug Discovery Centers

Institute for Therapeutics Discovery and Development

Therapeutic Approaches: Small Molecules,

Therapeutic Areas of Expertise: Infectious Diseases, Neurological Disorders, Oncology, Ophthalmology, Psychiatric Disorders, Pain, HIV, Non-Hormonal Male Contraception, Infectious Diseases

Center/Program Highlights:

The Institute for Therapeutics Discovery and Development (ITDD) is a research center within the College of Pharmacy with a mission to enhance the biomedical research infrastructure and create opportunities for drug discovery and early pre-clinical drug development through interdisciplinary research collaboration between various schools, colleges, and research centers.

The Institute consists of five scientific cores: Medicinal Chemistry, High-Throughput Screening, Lead and Probe Discovery, Chemical Process Development, and Preclinical Pharmacology

Institute’s state-of-the-art research facilities include chemical and biological laboratories, analytical laboratory, NMR and MS laboratories, API manufacturing suite, kilogram scale synthetic laboratory, high-throughput screening laboratory, cell-culture laboratory, and biological safety level 3 (BSL 3) facility. The Institute offers scientific services and collaborations in synthetic and medicinal chemistry, protein structure-based and computational drug design, protein-based, cell-based and high-content high-throughput screening (HTS), HTS assay development, design, rapid synthesis and high-throughput purification and analysis of novel chemical libraries, chemical processes development and optimization, scale-up, API manufacturing under GMP conditions and analytical method development, and preclinical pharmacology.

Sources of Funding: Federal/State, Philanthropy, Industry Partnerships, University, Revenue