Drug Discovery Centers

Center for Integrative Chemical Biology and Drug Discovery

Therapeutic Approaches: Small Molecules

Therapeutic Areas of Expertise: Oncology, chromatin regulation

Center/Program Highlights:

The Center was initiated with funding from across the University and a significant contribution from the University Cancer Research Fund (created by the State Legislature).

The goals of the Center are to:

• Enable interrogation of biology with small molecules resulting in funding of new UNC grant proposals


• Deliver 1 or more chemical probes or leads per year
• Establish external collaborations and funding base such that the Center is sustainable
• Create strong research program in chemical biology of chromatin regulation within the Center that competes effectively for external funding
• Create mechanisms for student and faculty training and enrichment in the areas of expertise within the Center
• Create collaborations and intellectual property to translate discoveries to patients

Sources of Funding: Federal/State, Philanthropy, University