Drug Discovery Centers

University of Colorado Denver High Throughput and High Content Screening Core

Therapeutic Approaches: Small Molecules, Biomarkers, Drug Delivery

Therapeutic Areas of Expertise: Cardiology, Immunology, Infectious Diseases, Metabolic Disorders, Neurological Disorders, Oncology, Regenerative Medicine

Center/Program Highlights:

The High Throughput and High Content Screening (HTS/HCS) Core Facility specializes in chemical biology as it relates to drug discovery, biological probe discovery, and phenotypic characterization of small-molecule effects on cellular systems. In addition to housing the instrumentation and robotics required for traditional HTS, the Core houses a cutting-edge High Content image-based system for next-generation small-molecule discovery research and analysis in fixed or live cells and cellular systems.

We have a number of compound libraries including annotated libraries (FDA approved drugs, NCI Oncology, SelleckChem Kinase) as well as a 20,0000 compound diversity library.

Sources of Funding: Philanthropy, Industry Partnerships, University, Revenue, Federal/State,