Drug Discovery Centers

TuCADD Tuebingen Center for Academic Drug Discovery

Therapeutic Approaches: Small Molecules,

Therapeutic Areas of Expertise: Immunology, Oncology, Regenerative Medicine

Center/Program Highlights:

Our centre combines strong expertises in RNAi based target discovery, modelling/virtual screening and medicinal chemistry. New therapeutic targets (main programs: cancer and regenerative medicine) are functionally identified via in vitro or in vivo shRNA screening. Prioritized targets are subjected to thorough functional validation in predictive preclinical mouse models. Genetically validated targets are then subjected to an established virtual screening plattform. Hits can be validated by re-synthesis and wet lab assays. The centre has access to fully established medicinal chemistry units with a track record of 3 first into man projects.
Further information can be found at
http://www.medchem.uni-tuebingen.de/

Sources of Funding: Federal/State, University