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E-Book
Assay Guidance Manual

The collection of chapters in this eBook is written to provide guidance to investigators who are interested in developing assays useful for the evaluation of collections of molecules to identify probes that modulate the activity of biological...

collaboration among group of editors and writers

multiple

Presenter: Sittampalam GS, Gal-Edd N, Arkin M, Auld D, Austin C, Bejcek B, Glicksman M, Inglese J, Lemmon V, Li Z, McGee J, McManus O, Minor L, Napper A, Riss T, Trask OJ , Weidner J, editors.

Video
Can we Treat MS?

Current therapies for MS, an autoimmune neuroinflammatory disease, target the immune part of the disease but current drug discovery efforts focus on treating and even reversing progressive disease. Check out the recent discussion on new research and...

Charles River

Presenter: Antti Nurmi, PhD, Director of Science
Document
Case Study: The Discovery of Telaprevir (VX-950, Incivek) for the treatment of Hepatitis C

This Case study shows the drug discovery process of Telaprevir for Hepatitis. IT discusses the background of Hepatitis, and the basic information on Hepatitis C, Preclinical studies, Clinical studies, critical findings, timeline to approval and the...

Brain Science Institute NeuroTranslational Drug Discovery Program

Johns Hopkins University

Presenter: Dana Ferraris, Ph.D., M.B.A.
PPT
In Vitro Pharmacokinetics

A lecture discussing In vitro Pharmacokinetics assays including permeability, metabolism, drug-drug interaction, and protein binding.

This is the fifth lecture in a 15-week course, Introduction to Drug Discovery Research, given at Johns Hopkins...

Brain Science Institute NeuroTranslational Drug Discovery Program

Johns Hopkins University

Presenter: Takashi Tsukamoto, Ph.D.
PPT
In Vitro Pharmacology I

A lecture discussing the general background of In Vitro Pharmacology and the two different target-based assays: enzymatic and Receptor.

This is the third lecture in a 15-week course, Introduction to Drug Discovery Research, given at Johns Hopkins...

BSi NeuroTranslational Drug Discovery Program

Johns Hopkins University

Presenter: Camilo Rojas, Ph.D.
PPT
In Vitro Pharmacology II

A lecture discussing Phenotype-Based Assays, High Throughput Screening, and Weeding out undesirable hits in In Vitro Pharmacology.

This is the fourth lecture in a 15-week course, Introduction to Drug Discovery Research, given at Johns Hopkins...

Brain Science Institute NeuroTranslational Drug Discovery Program

Johns Hopkins University

Presenter: Camilo Rojas, Ph.D.
PPT
The Small Molecule Discovery Center

This presentation introduces the Small Molecule Discovery Center at UCSF, and describes the center’s goals, philosophy, and examples of projects. Several different approaches to interacting with pharmaceutical companies are also summarized.

Small Molecule Discovery Center

University of California San Francisco

Presenter: Michelle Arkin